Description

CJC-1295 without DAC research material is supplied for laboratory and non-clinical investigation of CJC-1295 without DAC, a growth hormone-releasing hormone (GHRH) analog studied extensively in pituitary-signaling and endocrine research models.

What Is CJC-1295 Without DAC Research Material?

CJC-1295 without DAC is a synthetic 29-amino-acid analog of GHRH, modified for enhanced enzymatic stability but lacking the Drug Affinity Complex (DAC) modification that extends half-life, giving it a research profile closer to native GHRH pulsatility. CJC-1295 without DAC research material is used by laboratories investigating GHRH-receptor activation, pulsatile growth-hormone release patterns, and downstream endocrine signaling across in vitro and animal-model research systems.

Research Applications (laboratory / non-clinical research only)

• Animal model research into GHRH-receptor activation and pituitary signaling
• In vitro studies of pulsatile growth-hormone secretion mechanisms
• Preclinical investigation of short-acting GHRH-analog pharmacokinetic modeling
• Comparative research into CJC-1295 without DAC versus DAC-modified analog compounds
• Laboratory studies of somatotroph cell response in the anterior pituitary

Quality & Sourcing

CJC-1295 without DAC research material is manufactured to high purity standards and verified by HPLC (High-Performance Liquid Chromatography) analysis. Each batch is lyophilized for stability, and a Certificate of Analysis (COA) is available on request confirming peptide identity and purity. Material is intended for use by qualified researchers in controlled laboratory environments only.

Supplied As

Supplied as a lyophilized vial in a 3ml format, suitable for standard laboratory reconstitution procedures performed by trained personnel for research purposes.

Molecular Characteristics

CJC-1295 without DAC is a 29-amino-acid synthetic analog of GHRH, modified at several residues to improve resistance to enzymatic degradation while intentionally omitting the Drug Affinity Complex modification present in the extended-release variant. This gives the compound a research profile closer to native GHRH pulsatility, which researchers note is relevant when designing studies intended to model physiological pulsatile release patterns rather than sustained receptor activation, consistent with findings reported in the peer-reviewed research literature on this compound. The peptide is generally supplied as a lyophilized powder to maintain stability during storage.

Handling & Storage Considerations

Lyophilized CJC-1295 without DAC should be stored in a freezer (-20°C or below), protected from light and moisture, until the researcher is ready to reconstitute the material for a laboratory protocol. Once reconstituted with bacteriostatic water, the solution is generally stored refrigerated (2-8°C) and used within a relatively short window, as the compound’s shorter half-life relative to the DAC-modified variant is generally reported to correspond with reduced solution stability over time. Repeated freeze-thaw cycles are generally avoided to preserve research-grade integrity.

Common Research Design Considerations

Laboratories investigating CJC-1295 without DAC commonly design animal-model studies evaluating pulsatile growth-hormone release patterns and GHRH-receptor pharmacokinetics, often using shorter observation intervals than studies involving the DAC-modified variant. In vitro research frequently uses pituitary cell culture systems to characterize somatotroph cell response and receptor activation kinetics. Comparative study designs often examine CJC-1295 without DAC alongside the DAC-modified formulation and other GHRH-analog compounds to characterize differences in pharmacokinetic profile and pathway engagement.

Frequently Asked Questions

Is this compound stable at room temperature?
Short-term handling at room temperature during active laboratory use is generally acceptable, but frozen storage is recommended between research sessions to preserve peptide integrity.

What purity level should researchers expect?
Material is verified by HPLC analysis at the time of batch testing, with purity data available via the accompanying Certificate of Analysis.

Is a Certificate of Analysis provided?
Yes, a COA is available on request for each batch of CJC-1295 without DAC research material, confirming identity and purity for research documentation purposes.

Related Compounds

Researchers investigating CJC-1295 without DAC often also study ipamorelin, as the two peptides are frequently examined together in growth-hormone axis research, including the combination formulation available in the catalog.

Summary
CJC-1295 without DAC research material offers laboratories a shorter-acting GHRH analog option for studying pulsatile growth-hormone release patterns. This CJC-1295 without DAC research formulation is supplied strictly for laboratory research use, with HPLC verification and COA documentation supporting research-grade traceability.

For research use only. Not for human or veterinary use. Not a drug, supplement, or therapeutic product. Not intended to diagnose, treat, cure, or prevent any condition.