Description
PT-141 bremelanotide research material is supplied for laboratory and non-clinical investigation of PT-141 (bremelanotide), a synthetic cyclic heptapeptide studied extensively in melanocortin-receptor signaling research models.
What Is PT-141 Bremelanotide
PT-141 is a synthetic analog of the naturally occurring hormone alpha-melanocyte-stimulating hormone (alpha-MSH), structurally modified for receptor-binding research applications. PT-141 bremelanotide research material is used by laboratories investigating melanocortin receptor subtype activation (MC3R and MC4R), central nervous system signaling pathways, and downstream physiological response mechanisms across in vitro and animal-model research systems.
Research Applications (laboratory / non-clinical research only)
- Animal model research into melanocortin receptor (MC3R/MC4R) activation pathways
- In vitro studies of central nervous system receptor-binding kinetics
- Preclinical investigation of melanocortin-pathway signaling in rodent models
- Comparative research into alpha-MSH analog compounds and receptor selectivity
- Laboratory studies of pigmentation-pathway research models
Quality & Sourcing
PT-141 bremelanotide research material is manufactured to high purity standards and verified by HPLC (High-Performance Liquid Chromatography) analysis. Each batch is lyophilized for stability, and a Certificate of Analysis (COA) is available on request confirming peptide identity and purity. Material is intended for use by qualified researchers in controlled laboratory environments only.
Supplied As
Supplied as a lyophilized 10mg vial in a 3ml format, suitable for standard laboratory reconstitution procedures performed by trained personnel for research purposes.
Molecular Characteristics
PT-141 (bremelanotide) is a synthetic cyclic heptapeptide analog of alpha-melanocyte-stimulating hormone, modified to activate melanocortin receptor subtypes MC3R and MC4R. The cyclic structure, stabilized by an internal bond between residues, is generally reported in the literature to confer greater resistance to enzymatic degradation than linear peptide analogs. As a modestly sized cyclic peptide, PT-141 is typically supplied as a lyophilized powder to preserve this structure during storage and shipping.
Handling & Storage Considerations
Lyophilized PT-141 should be stored in a freezer (-20°C or below), protected from light and moisture, until the researcher is ready to reconstitute the material for a laboratory protocol. Once reconstituted with bacteriostatic water, the solution is generally stored refrigerated (2-8°C) and used within the window supported by internal stability testing. As with other melanocortin-receptor research peptides, repeated freeze-thaw cycles and prolonged room-temperature exposure are generally avoided to preserve research-grade integrity.
Common Research Design Considerations
Laboratories investigating PT-141 commonly design animal-model studies evaluating melanocortin receptor activation and downstream central nervous system signaling pathways in rodent models. In vitro research frequently uses receptor-binding assays to characterize MC3R and MC4R subtype selectivity and binding kinetics. Comparative study designs often examine PT-141 alongside other alpha-MSH analog compounds to characterize differences in receptor selectivity and downstream pathway engagement within the same laboratory program.
Frequently Asked Questions
Is this compound stable at room temperature?
Short-term handling at room temperature during active laboratory use is generally acceptable, but frozen storage is recommended between research sessions to preserve peptide integrity.
What purity level should researchers expect?
Material is verified by HPLC analysis at the time of batch testing, with purity data available via the accompanying Certificate of Analysis.
Is a Certificate of Analysis provided?
Yes, a COA is available on request for each batch, confirming identity and purity for research documentation purposes. Documentation is provided in a format suitable for laboratory recordkeeping and internal quality assurance processes.
Related Compounds
Researchers investigating PT-141 in melanocortin-receptor research contexts often also study Oxytocin Acetate, another neuropeptide-related compound examined within comparative laboratory programs on central nervous system receptor signaling. Comparative panels involving several melanocortin and neuropeptide receptor compounds are common in laboratories characterizing receptor subtype selectivity across this broader research category. This comparative approach supports a more complete understanding of receptor pharmacology within the melanocortin research field, including mood-and-neuropeptide research involving Selank.
For research use only. Not for human or veterinary use. Not a drug, supplement, or therapeutic product. Not intended to diagnose, treat, cure, or prevent any condition.
