Description

SS-31 50mg peptide research material is supplied for laboratory and non-clinical investigation of SS-31 (elamipretide, also referenced as MTP-131), a synthetic mitochondria-targeted tetrapeptide studied in mitochondrial bioenergetics and longevity research models.

What Is SS-31

SS-31 is a short, cell-permeable Szeto-Schiller peptide built around an alternating aromatic-cationic motif (D-Arg-Dmt-Lys-Phe-NH2). In published research it is described as concentrating at the inner mitochondrial membrane, where it associates with cardiolipin, a phospholipid central to electron transport chain organization. SS-31 50mg peptide research material is used by laboratories investigating mitochondrial membrane integrity, cristae structure and oxidative stress in in vitro and animal-model research systems.

Research Applications (laboratory / non-clinical research only)

• In vitro studies of cardiolipin interactions and inner mitochondrial membrane organization
• Animal model research into mitochondrial bioenergetics and ATP production
• Preclinical investigation of reactive oxygen species and oxidative stress pathways
• Comparative research alongside other mitochondrial-targeted compounds such as MOTS-c and NAD+
• Laboratory studies of mitochondrial function in aging and cellular stress models

Quality & Sourcing

SS-31 peptide research material is manufactured to high purity standards and verified by HPLC (High-Performance Liquid Chromatography) analysis. Each batch is lyophilized for stability, and a Certificate of Analysis (COA) is available on request confirming peptide identity and purity. Material is intended for use by qualified researchers in controlled laboratory environments only.

Supplied As

Supplied as a lyophilized 50mg vial, suitable for standard laboratory reconstitution procedures performed by trained personnel for research purposes.

Molecular Characteristics

SS-31 is a synthetic tetrapeptide (D-Arg-Dmt-Lys-Phe-NH2) with a molecular formula of C32H49N9O5 and a molecular weight of approximately 640 g/mol. The inclusion of the non-natural amino acid 2′,6′-dimethyltyrosine (Dmt) and a D-amino acid contributes to its stability in research settings. It is supplied as a lyophilized powder to preserve integrity during storage.

Handling & Storage Considerations

Lyophilized SS-31 should be stored in a freezer (-20°C or below), protected from light and moisture, until it is required for a laboratory protocol. Once reconstituted for research use, material should be kept refrigerated (2-8°C) and used within the timeframe defined by the laboratory’s own stability testing. Avoid repeated freeze-thaw cycles.

Common Research Design Considerations

Laboratories investigating SS-31 commonly measure mitochondrial respiration, membrane potential and markers of oxidative damage, and frequently compare it with untreated controls and with other mitochondrial-active compounds to isolate cardiolipin-related effects.

Frequently Asked Questions

Is SS-31 the same as elamipretide?
Yes. SS-31, elamipretide and MTP-131 are names used in the scientific literature for the same tetrapeptide.

Is a COA available?
Yes, a Certificate of Analysis is available on request for each batch, confirming identity and purity.

For laboratory research use only. Not for human or veterinary use. Not a drug, food or cosmetic, and not evaluated by the FDA.